Verified Performance Tests Updated May 2026 · 3 recorded runs

Mercedes-Benz S580 0–60 Times

The Mercedes-Benz S580 0–60 times and quarter-mile times below are from 3 recorded performance tests sourced from reputable automotive resources such as Car and Driver and Motor Trend and more.

The fastest tested Mercedes-Benz S580 is the 2021 Mercedes-Benz S580 AMG Line Night 4MATIC Sedan, which went from 0 to 60 mph in 3.90 seconds, reaching the ¼ mile in 12.50 seconds at 114.0 mph, according to Car and Driver.

The slowest tested Mercedes-Benz S580 is the 2021 Mercedes-Benz S580 AMG Line Night 4MATIC Sedan, which took 4.00 seconds to reach 60 mph, running the ¼ mile in 12.50 seconds at 113.2 mph, according to Motor Trend.

Out of all the Mercedes-Benz S580 tests in our database, the average 0–60 mph time is 3.97 seconds. The average quarter-mile time is 12.50 seconds at 113.37 mph.

Fastest 0–60 3.90sec 2021 AMG Line Night 4MATIC Sedan · stock
Average 0–60 3.97sec Across 3 runs
Avg ¼ Mile 12.50sec @ 113.4 mph trap
Slowest 0–60 4.00sec 2021 AMG Line
2021 Mercedes-Benz S580

Across 3 verified runs, the Mercedes-Benz S580 ranges from 3.90 to 4.00 seconds 0–60, with a 3.97-second average.

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Mercedes-Benz S580 Performance Overview

For the Mercedes-Benz S580, the performance record currently centers on a single launch year, with 3 verified tests spanning 2021 to 2021. In W223 form, the S580 established its measurable baseline immediately: all recorded runs come from the 2021 AMG Line Night 4MATIC Sedan, using the 496-hp M176-based hybrid powertrain. That combination places the model in the upper four-second to high three-second range, with recorded 0-60 times from 4.0 to 3.9 seconds, and a fastest quarter-mile of 12.5 seconds at 114 mph.

Because the available test history covers only 2021, the model's performance evolution is defined by consistency rather than multi-era change. The quickest benchmark was set by the 2021 AMG Line Night 4MATIC Sedan at 3.9 seconds to 60 mph, while another verified run for the same trim returned 4.0 seconds, and the average across all three tests settled at 3.97 seconds. Quarter-mile results averaged 12.5 seconds at 113.4 mph. As it stands today, the current W223-generation S580 remains represented in this dataset exclusively by a hybrid, all-wheel-drive configuration, with the 2021 AMG Line Night 4MATIC Sedan also serving as the current-generation best at 3.9 seconds to 60 mph.

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Mercedes-Benz S580 0–60 Times by Generation

1 generation
Generation Years Avg 0–60 Fastest 0–60 Tests Notes
W223 2021–present 3.97s 3.90s — 2021 AMG Line Night 4MATIC Sedan 3 The W223 generation (2021–present) averaged 3.97 seconds to 60 mph across 3 tests, led by the 2021 AMG Line Night 4MATIC Sedan at 3.90 seconds. Output was 496 hp across 4.0L Twin-Turbo V8 + Elec configurations.
W223 2021–present
Avg 0–60 3.97s
Fastest 3.90s
Tests 3
2021 AMG Line Night 4MATIC Sedan
The W223 generation (2021–present) averaged 3.97 seconds to 60 mph across 3 tests, led by the 2021 AMG Line Night 4MATIC Sedan at 3.90 seconds. Output was 496 hp across 4.0L Twin-Turbo V8 + Elec configurations.
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Mercedes-Benz S580 0–60 Times by Year and Trim

3 tests · 1 year

2021 Mercedes-Benz S580

3 verified runs
Avg 0–60 3.97 sec
Avg ¼ Mile 12.50 sec
Recorded Tests 3
#01
2021 Mercedes-Benz S580 AMG Line Night 4MATIC Sedan
3.90sec 0–60
0.0s · 0mph 0.0s · 0mph
12.50s ¼ mi @ 114.0 mph
0–60 mph
3.90 sec
¼ Mile ET
12.50 sec
Trap Speed
114.0 mph
Engine
4.0L Twin-Turbo V8 + Elec
Drivetrain
AWD
Transmission
9A
Horsepower
496 hp
Torque
516 lb-ft
Curb Weight
4,784 lbs
Power-to-Weight
9.6 lbs/hp
MPG EPA
17 C / 25 H / 20 Obs
Production Vehicle
Production
Body Type
Sedan
Powertrain
Hybrid
Test Source
Car and Driver
Overall Rank
#1 of 3
2021 Mercedes-Benz S580 AMG Line Night 4MATIC Sedan
#02
2021 Mercedes-Benz S580 AMG Line Night 4MATIC Sedan
4.00sec 0–60
0.0s · 0mph 0.0s · 0mph
12.50s ¼ mi @ 113.2 mph
0–60 mph
4.00 sec
¼ Mile ET
12.50 sec
Trap Speed
113.2 mph
Engine
4.0L Twin-Turbo V8 + Elec
Drivetrain
AWD
Transmission
9A
Horsepower
496 hp
Torque
516 lb-ft
Curb Weight
4,784 lbs
Power-to-Weight
9.6 lbs/hp
MPG EPA
17 C / 25 H
Production Vehicle
Production
Body Type
Sedan
Powertrain
Hybrid
Test Source
Motor Trend
Overall Rank
#2 of 3
2021 Mercedes-Benz S580 AMG Line Night 4MATIC Sedan
#03
2021 Mercedes-Benz S580 AMG Line Night 4MATIC Sedan
4.00sec 0–60
0.0s · 0mph 0.0s · 0mph
12.50s ¼ mi @ 112.9 mph
0–60 mph
4.00 sec
¼ Mile ET
12.50 sec
Trap Speed
112.9 mph
Engine
4.0L Twin-Turbo V8 + Elec
Drivetrain
AWD
Transmission
9A
Horsepower
496 hp
Torque
516 lb-ft
Curb Weight
4,784 lbs
Power-to-Weight
9.6 lbs/hp
MPG EPA
17 C / 25 H
Production Vehicle
Production
Body Type
Sedan
Powertrain
Hybrid
Test Source
Motor Trend
Overall Rank
#3 of 3
2021 Mercedes-Benz S580 AMG Line Night 4MATIC Sedan

How we verify Mercedes-Benz S580 performance data

We include only independently published road-test results from automotive publications. Manufacturer-claimed 0–60 times are excluded unless clearly labeled. When multiple publications test the same Mercedes-Benz S580 trim, each run is listed separately — weather, tires, surface, rollout, and instrumentation all affect results.

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Mercedes-Benz S580 0–60 and quarter-mile distribution

0–60 vs ¼ mile · lower-left is faster
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Mercedes-Benz S580 performance FAQs

9 questions
The 2021 Mercedes-Benz S580 reaches 60 mph in 3.9 to 4.0 seconds across three verified stock tests. The quickest run for the AMG Line Night 4MATIC Sedan is 3.9 seconds, while the average across all recorded tests is 3.97 seconds. Quarter-mile performance averages 12.5 seconds at 113.4 mph.
The quickest Mercedes-Benz S580 on record is a 2021 AMG Line Night 4MATIC Sedan at 3.9 seconds from 0 to 60 mph. That same car also holds the best quarter-mile result, running 12.5 seconds at 114 mph. All recorded S580 tests are stock, so the overall fastest and fastest stock result are the same.
The fastest stock Mercedes-Benz S580 tested so far is the 2021 AMG Line Night 4MATIC Sedan, with a 0-60 time of 3.9 seconds. Since all three recorded S580 runs are stock production cars, there is no modified result to separate from the production benchmark. Its best quarter-mile is 12.5 seconds at 114 mph.
The Mercedes-Benz S580 runs the quarter mile in 12.5 seconds in every recorded test. Trap speed ranges from 112.9 mph to 114 mph, with an overall average of 113.4 mph. The quickest trap is 114 mph from the 2021 AMG Line Night 4MATIC Sedan, which is also the fastest 0-60 S580 on record.
The W223 Mercedes-Benz S580 posts a 3.97-second average 0-60 time across three verified runs. Its quickest recorded sprint is 3.9 seconds, set by the 2021 AMG Line Night 4MATIC Sedan. Every W223 S580 test currently on record is a hybrid, AWD sedan with 496 horsepower and 516 lb-ft of torque.
The fastest W223 Mercedes-Benz S580 is the 2021 AMG Line Night 4MATIC Sedan, which reaches 60 mph in 3.9 seconds. That is the best result among all three W223 S580 tests on record. It also records the top quarter-mile trap at 114 mph while matching the class-best 12.5-second elapsed time.
Yes. A 3.9 to 4.0 second 0-60 time is very quick for a full-size luxury sedan weighing 4,784 pounds. The 2021 S580 combines 496 horsepower, 516 lb-ft, hybrid assistance, and AWD traction to deliver strong launch performance. Its 12.5-second quarter-mile further confirms that it is genuinely fast, not just quick off the line.
There are 3 recorded Mercedes-Benz S580 acceleration tests, and all 3 are stock production cars. Across those runs, the average 0-60 time is 3.97 seconds. Quarter-mile performance averages 12.5 seconds at 113.4 mph, with the quickest 0-60 result being 3.9 seconds.
The quickest Mercedes-Benz S580 tested uses the M176 engine in a hybrid powertrain. In the 2021 AMG Line Night 4MATIC Sedan, output is listed at 496 horsepower and 516 lb-ft of torque. That setup helps the AWD sedan reach 60 mph in as little as 3.9 seconds and run the quarter mile in 12.5 seconds.

Sources

Car and Driver
Motor Trend

0–60 and quarter-mile times vary with driver, weather, tire temperature, and wear. We collect every verified run we can find — so you see the range of what a Mercedes-Benz S580 can do, not a single marketing claim.

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Other Mercedes-Benz 0–60 times

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